2019, Volume 11, Issue 4
The incidence and the type of stomatognathic disorders in patients with Gardner syndrome. A systematic review
Olga Preuss1, Aleksandra Jaroń1, Anna Grzywacz2, Magda Aniko-Włodarczyk1, Grzegorz Trybek1
1Department of Oral Surgery, Pomeranian Medical University in Szczecin
2Independent Laboratory of Health Promotion, Pomeranian Medical University in Szczecin
Author for correspondence: Aleksandra Jaroń; Department of Oral Surgery, Pomeranian Medical University in Szczecin; email: firstname.lastname@example.org
Background: Diseases of genetic origin are very often associated with oral disorders. One of them is Gardner syndrome (GS) a rare variant of familial adenomatous polyposis (FAP), whose main manifestation is colon cancer. Its most common oral cavity symptoms include osteomas, odontomas and impacted or supernumerary teeth.
Material and methods: Medline (PubMed), Medline (Ebsco), Scopus and Google Scholar databases were searched oral manifestations of Gardner Syndrome.
Results: Thirty-eight articles met inclusion criteria. The most frequently mentioned oral changes included osteomas, impacted teeth, supernumerary teeth and odontomas.
Conclusion: This review provides evidence for associating FAP with oral disorders. Dentists can be the first doctor able to diagnose Gardner Syndrome and refer patients for systemic treatment. The incidence of changes in the oral cavity is significant and should be considered as an indication of Gardner Syndrome.
Key words: Gardner Syndrome, oral lesions, cancer