2018, Volume 10, Issue 4
The effect of vitamin D3 on the osteointegration of dental implant
Grzegorz Trybek1, Magda Aniko-Włodarczyk1, Jakub Kwiatek1, Olga Preuss1, Andrzej Brodkiewicz2, Andrzej Sinicyn3, Anna Grzywacz4
1Oral Surgery Department, Pomeranian Medical University
2 Department of Pediatric, Child Nephrology, Dialysotheraphy and Management of Acute Poisoning, Pomeranian Medical University
3Trauma and Orthopaedic Unit, Independent Public Health Care Centre in Świdnica
4Independent Laboratory of Health Promotion, Pomeranian Medical University
Author for correspondence: Magda Aniko-Włodarczyk; Oral Surgery Department, Pomeranian Medical University; email: firstname.lastname@example.org
Dental surgeons, maxillofacial surgeons and implantologists are increasingly interested in the effects of vitamin D on bone metabolism and the immune system. The correct concentration of this prohormone potentially correlates with success at each stage of osteointegration of endosseous implants.
A review of literature related to the topic of the paper.
A suitable level of vitamin D3 is crucial from the day of surgery. It influences the modulation of the immune system – increases the production of cathelicidin and defensin, and reduces the expression of proinflammatory cytokines. It also has a positive effect on bone metabolism in osteo-suppression via the induction of osteoblasts and osteoclasts and continuous bone remodeling around the implant after prosthetic restoration.
The prevalence of low vitamin D levels in the European population leads to the conclusion that a high deficit is not a factor directly responsible for failures in the process of osteointegration.
Key words: vitamin D3, calcitriol, osteointegration of implants